Intermediate Word:  applique (a) transfer applied with a hot iron  (b) decorative cloth sewn on other cloth  (c) decorative painting  (d) poultice
Difficult Word:
  hornpout - (a) North African antelope  (b) angry intransigence  (c) ivory tribal horn  (d) greshwater catfish

NSAIDs include COX-2 inhibitors and ibuprofen Heart attack risk with pain drugs  - BBC  People taking high daily doses of two common painkillers are at increased risk of heart attack and stroke, say Oxford researchers. The researchers stressed that the overall risk was small - for every 1,000 patients taking a COX-2 or an NSAID around three extra people a year would have a heart attack. The odds were increased by 51% for high-dose ibuprofen (800mg three times a day) and 63% for high-dose diclofenac (75mg twice a day). Another NSAID - naproxen - was found not to be associated with an increased risk of cardiovascular events. for most people who don't have a history of heart attack or stroke the risk is very small.   
Niacin has been shown to increase HDL 'Good' cholesterol drug trialled  - BBC  A major international trial has been set up to see whether a treatment to increase so-called "good" cholesterol can prevent heart attacks and strokes. "Good" cholesterol - high density lipoproteins (HDL) - cuts heart disease risk removing fat from the circulation. The treatment, designed to increase levels of HDL, will be given alongside drugs to reduce "bad" cholesterol, which can raise the risk of disease. The main ingredient in the trial drug is niacin, which has been found to increase levels of HDL by between a fifth and a quarter as well as decreasing dangerous fatty substances called triglycerides.   

Grey gamers flex brain muscles  - BBC  In Japan's rapidly ageing society, more and more older people are looking for ways to keep them active and alert for longer. Electronic games makers have responded with new products designed to train your brain. Electronic games makers have responded with new products designed to train your brain. The teacher who came to this himself quite late on is Atsuo Umetsu. He is showing his pupils how to play a game that tests your mathematics ability. After a few minutes of gentle encouragement, they start to get the hang of it as most of the grey gamers are grinning. It is a craze that has Japan hooked.

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